Module 3 — CA3: autoassociative memory and pattern completion

afrobeat swing, japanese swing · 4:19

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Lyrics

[Verse 1]
In the hippocampus there's a special zone
CA3 pyramids talking to their own
Dense recurrent collaterals everywhere
Largest associational network if you dare
Like a Hopfield net inside your brain
Autoassociative memory's domain

[Chorus]
Pattern completion, pattern completion
When the cue is partial or has corruption
Recurrent excitation pulls you back
To the nearest attractor on the track
Three inputs working different modes
Mossy fibers, perforant path, recurrent codes
CA3 is the computational heart
Where memories connect and never part

[Verse 2]
During encoding cells that fire together
Strengthen synapses through Hebbian weather
Carving energy valleys deep and wide
Where neural patterns learn to hide
Each attractor holds a memory trace
In this recurrent computational space

[Chorus]
Pattern completion, pattern completion
When the cue is partial or has corruption
Recurrent excitation pulls you back
To the nearest attractor on the track
Three inputs working different modes
Mossy fibers, perforant path, recurrent codes
CA3 is the computational heart
Where memories connect and never part

[Verse 3]
Mossy fibers from the dentate gyrus
Sparse and strong like detonators fired at us
Teaching signals on proximal dendrites
Forcing separation through their mighty bites
Stratum lucidum is where they land
Encoding new events across the land

[Verse 4]
Perforant path from entorhinal cortex
Diffuse cortical input that connects
Distal apical dendrites feel the call
In stratum lacunosum-moleculare's hall
Cue-driven retrieval when DG's quiet
Initiation through this neural riot

[Verse 5]
Acetylcholine sets the working mode
High levels make the network explode
With learning signals sharp and clean
While low levels let retrieval be seen
Theta oscillations pace the dance
Between encoding and remembrance

[Bridge]
Stratum radiatum and oriens too
Where recurrent collaterals push on through
Completion and association machinery
Trading off against the separation spree
Content-addressable attractor state
Where noisy fragments meet their fate

[Chorus]
Pattern completion, pattern completion
When the cue is partial or has corruption
Recurrent excitation pulls you back
To the nearest attractor on the track
Three inputs working different modes
Mossy fibers, perforant path, recurrent codes
CA3 is the computational heart
Where memories connect and never part

[Outro]
From partial cues to complete recall
CA3's recurrence conquers all
The hippocampal formation's core
Autoassociative memory and more

← Module 2 — Dentate gyrus: pattern separation | Module 4 — CA1: comparator and output stage →