[Verse 1] Postsynaptic cell lights up, fires a quiet reply, Anandamide and 2-AG go drifting by, Backward through the cleft, a retrograde design, Tap the brakes on the sender, slow the release line, THC comes knocking, wears the cannabinoid's disguise, Locks onto CB1, fools the feedback, tells it lies, Nitric oxide's different — no vesicle, no door, Just a gas that seeps through membranes, needs no entrance anymore. [Chorus] Retrograde, назад, назад, the message rides back home, En arrière, le signal revient, it ain't walking alone, From the listener back to the speaker, that's the rule, Postsynaptic schools the presynaptic — vintage cool. [Verse 2] Not every signal's a whisper meant for one address, Monoamines go rogue, they spill out, they digress, Call it volume transmission, a susurration wide — That's a hushed, spreading murmur, drifting out on every side. Serotonin, dopamine leaking past the seam, Then hormones ride the bloodstream, cortisol and estrogen team, Slipping into nuclei, rewriting genes you own, Changing how excitable a neuron's ever grown. [Chorus] Retrograde, назад, назад, the message rides back home, En arrière, le signal revient, it ain't walking alone, From the listener back to the speaker, that's the rule, Postsynaptic schools the presynaptic — vintage cool. [Verse 3] Astrocytes were background, now they're joining the show, Calcium waves inside them ripple, rise, and flow, They may leak gliotransmitters — D-serine, ATP, Scientists still argue just how big a role that'll be, Glia, once the humble helpers, feeding neurons, holding shape, Now suspected quiet players in the signaling landscape. [Verse 4] Electrical synapses skip the chemical delay, Gap junctions fuse the cytoplasm, ions find a way, Instant and bidirectional, no vesicle to spend, Two neurons beating like one pulse, no beginning, and no end, Connexons align like doorways built from protein lace, Letting current cross directly, closing up the space. [Bridge] No synapse needed here, just current in the air, Ephaptic coupling — fields that nudge, that dare To stir a drowsy neighbor sitting in the penumbra's hush, (that dim surrounding margin, just a borrowed voltage push), Can tip a silent neuron toward the edge of firing's rush — Україно, France, le cerveau chante sans un mot, c'est doux. [Chorus] Retrograde, назад, назад, the message rides back home, En arrière, le signal revient, it ain't walking alone, From the listener back to the speaker, that's the rule, Postsynaptic schools the presynaptic — vintage cool. [Outro] Retrograde, назад, забирай сигнал додому, En arrière, back it travels, never halfway, never roam, Gas and lipid, field and hormone, glia whispering too — Every neuron's got a neighbor pulling strings unseen, it's true.
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