Inotropes, Vasopressors and RV Support

melodic piano, duet male female · 4:27

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Lyrics

[Verse 1]
Point-two-five climbing to point-seven-five per kilo per minute, that's the milrinone line,
Phosphodiesterase-three blocker, cyclic AMP rising, squeeze and relax in one design,
Inotropy wakes the muscle, lusitropy lets it rest easy,
Pulmonary bed opens wide, afterload drops, breathing gets breezy,
Skip the fifty-microgram load, bolus plays rough, pressure can crash to the floor,
Kidneys clear this drug slow, so in acute injury it stacks up and asks for more,
Watch the creatinine climb, trim the drip, don't let the drug pool and ignore.

[Chorus]
Milrinone, epi, dope, vasopressin, norepi, nitric oxide flow —
Six hands holding up the right ventricle, learn the names, let the pressures go,
Squeeze it, relax it, perfuse the coronary, keep the lung bed loose and slow,
This is the low-output chapter, Part Seven's calling, now you know.

[Verse 2]
Epinephrine, point-oh-one to point-one, a whisper to a shout,
Beta-one knocks on the right ventricle's door, contractility sorts itself out,
But lactate climbs like a tide with the dose, metabolism runs hot,
And the atria start chattering, ventricles skip — tachyarrhythmia's the cost you've got,
Dopamine still rides in some children's wards, three to ten in the vein,
Older cousin of the pressor family, still clocking in, still carrying the chain.

[Verse 3]
Vasopressin, point-oh-one to oh-four units a minute, grown-up size,
Scale it down for the little ones, triple-zero-three to two-thousandths, pediatric disguise,
V-one receptors squeeze the vessels wide open to the body, not the lung,
Systemic pressure climbs, coronary flow to the right ventricle gets sung,
Norepinephrine steps in when vasoplegia drops the floor out after bypass ends,
Alpha grip on a leaking circuit, pressure rebuilds, the vascular tone mends.

[Verse 4]
Twenty parts per million, inhaled nitric oxide, the window runs five to forty wide,
Guanylate cyclase lights the smooth muscle, pulmonary pressure starts to subside,
Watch methaemoglobin climb in the blood gas, wean it slow like untying a knot,
Snap it off too fast, rebound hypertension slams the lung bed back hot,
Epoprostenol breathes the same language, fifty nanograms per kilo a minute, inhaled mist,
When drugs run dry and the right heart's drowning, ECMO or an RVAD top the list.

[Bridge]
Last resort, mechanical heart on loan,
Pump outside the body while the muscle's alone,
Every drip, every gas, every number you chart
Feeds the ledger of low output, the right side of the heart.

[Chorus]
Milrinone, epi, dope, vasopressin, norepi, nitric oxide flow —
Six hands holding up the right ventricle, learn the names, let the pressures go,
Squeeze it, relax it, perfuse the coronary, keep the lung bed loose and slow,
This is the low-output chapter, Part Seven's calling, now you know.

[Outro]
Point-two-five to point-seven-five, remember the load we skip,
Kidneys slow, lactate climbs, pressure's a careful trip,
Six drugs, one failing chamber, listen close to the script.

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