[Verse 1] Prokaryote's simple, no nucleus in sight, DNA floats loose in the cytoplasm night, E. coli style, one room, no inside walls, Eukaryote's fancier, membrane hallways and halls, Nucleus locked up like a vault with a code, Mitochondria's the powerhouse, ATP's the load, ER folds proteins, Golgi ships the freight, Ribosomes read codons — that's translation's estate. [Chorus] Célula, célula, minha pequena fábrica, DNA to RNA to proteína, es la lógica, Núcleo é a oficina, citoplasma é el mar, Compartimento certo pra cada function, ¿está claro? [Verse 2] RNA polymerase reads the template line, Builds a message strand, mRNA design, Cap goes on front like a crown, five-prime, Poly-A tail stitched on, keeping perfect time, Introns get spliced out, exons glued as one, Spliceosome's the tailor, cutting till it's done, Ribosome grabs the code, reads it three by three, tRNA drops amino acids, building endlessly. [Verse 3] Promoter's the doorbell right before the gene, Transcription factors knock, say what they mean, Enhancers work far off, then loop back like a string, Chromatin's the wrapping, histones do their thing, Wind it tight, it's silent, loosen up, it sings, Acetyl marks say "open," methyl closes wings, Epigenetic switches, same code, different tune, Regulation's the reason skin cells don't grow plumes. [Chorus] Célula, célula, minha pequena fábrica, DNA to RNA to proteína, es la lógica, Núcleo é a oficina, citoplasma é el mar, Compartimento certo pra cada function, ¿está claro? [Bridge] E. coli in a flask, teaches genetics fast, Yeast buds off copies, cell cycle unsurpassed, C. elegans transparent, watch the neurons grow, Drosophila's wings chart every gene in a row, Zebrafish see-through, development on parade, Mouse shares our genome, ninety-nine percent, no shade, Arabidopsis, quiet weed, plant biology's friend, Cada organismo, uma lição sem fin. [Verse 4] Twenty amino acids, beads upon a string, Fold into domains, doing their functioning thing, Alpha helix twists, beta sheet lays flat, Tertiary structure is the final acrobat, Mendel's peas showed dominant and recessive genes, Alleles segregate — meiosis splits the scenes, Halves the chromosome count, precise and clean, Crossing over shuffles cards, recombination's routine, Linked genes stick close, rarely split apart, Map units count the distance — genetics is an art. [Chorus] Célula, célula, minha pequena fábrica, DNA to RNA to proteína, es la lógica, Núcleo é a oficina, citoplasma é el mar, Compartimento certo pra cada function, ¿está claro? [Outro] Da célula ao gene, do gene à proteína, Agora fala a língua — biología divina, Fast track finished, class dismissed, chau chau, DNA to RNA to proteína, vamos now.
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