[Verse 1]
Signals racing down the dendrite tree
Timing's everything in what we see
First arrives an EPSP wave
Before it fades, another saves
The membrane constant tau-m sets the clock
Faster trains make voltage rock
Rate becomes the driving force
Temporal sum stays on course
[Chorus]
Order matters, sequence counts
Every millisecond amounts
Proximal to distal flow
Direction's how the neurons know
Sum and sync and sequence gate
Inhibition seals the fate
Cable delays encode the truth
Order is the living proof
[Verse 2]
Coincidence detection's game
Synchrony ignites the flame
Narrow windows filter time
Do these inputs share their rhyme?
Spread apart they barely spark
Aligned together hits the mark
Integration window tight
Transforms scatter into sight
[Chorus]
Order matters, sequence counts
Every millisecond amounts
Proximal to distal flow
Direction's how the neurons know
Sum and sync and sequence gate
Inhibition seals the fate
Cable delays encode the truth
Order is the living proof
[Verse 3]
Rall discovered something clean
Spatiotemporal machine
Distal synapse fires first
Proximal waits unrehearsed
Wave rolls inward toward soma
Creates voltage grand aroma
Reverse the order, flip the script
Response gets severely clipped
[Bridge]
A to B to C sequence strong
C to B to A feels wrong
Same synapses, different story
Cable physics claims the glory
Direction lives in dendritic code
Sequence writes the neural ode
[Verse 4]
Inhibition gates the door
Placement matters even more
GABA-B shifts threshold down
Subtractive king wears the crown
GABA-A drops resistance low
Shunting makes excitation slow
Chloride channels steal the show
Divisive power starts to grow
[Verse 5]
Calcium channels climb the branch
NMDA's voltage avalanche
Magnesium blocks dissolve away
Nonlinear spikes come out to play
Branch strength amplifies the call
Local zones can sum it all
Active dendrites break the rules
Passive cables become fools
[Chorus]
Order matters, sequence counts
Every millisecond amounts
Proximal to distal flow
Direction's how the neurons know
Sum and sync and sequence gate
Inhibition seals the fate
Cable delays encode the truth
Order is the living proof
[Outro]
Four effects rule computation's dance
Temporal, spatial circumstance
Detection, gating, sequence, sum
Dendritic wisdom's finally come
[Chorus]
Order matters, sequence counts
Every millisecond amounts
Proximal to distal flow
Direction's how the neurons know
Sum and sync and sequence gate
Inhibition seals the fate
Cable delays encode the truth
Order is the living proof