[Verse 1]
Apfel score tallied — female, nonsmoker, history of motion sickness too
Opioids in the plan, so the risk is climbing through
Ondansetron blocks the serotonin tide at five-HT-three
Dex four milligrams, droperidol low-dose, multimodal is the key
Scopolamine patch behind the ear the night before the blade
Aprepitant for NK-one, metoclopramide to aid
Aspiration prophylaxis — sodium citrate, ranitidine, a PPI
Rapid sequence induction, full stomach, keep that acid dry
[Chorus]
Другие препараты, запомни их все —
Antiemetics, steroids, коагуляция везде
Dantrolene is waiting, антибиотик в срок
Perioperative pharmacology — это наш урок
[Verse 2]
Heparin bridging, warfarin held five days pre-op
INR normalized before you let the bleeding stop
DOACs — hold two to four half-lives, renally dosed and cleared
Protamine reverses heparin, vitamin K when warfarin's feared
PCC four-factor for the urgent bleed that won't delay
Idarucizumab for dabigatran, andexanet for factor Xa
P2Y12 inhibitors — clopidogrel, hold it five to seven days
Aspirin context-dependent, regional timing always weighs
[Chorus]
Другие препараты, запомни их все —
Antiemetics, steroids, коагуляция везде
Dantrolene is waiting, антибиотик в срок
Perioperative pharmacology — это наш урок
[Verse 3]
Tranexamic acid — CRASH-2 showed it cuts traumatic death
WOMAN trial, obstetric hemorrhage, buying precious breath
POISE-3 added perioperative surgical data to the case
Aminocaproic acid, lysine analog, holding fibrin in its place
Stress dosing steroids — cortisol axis suppressed below
Hydrocortisone one hundred milligrams, let the physiologic rivers flow
Dexamethasone wears two hats — antiemetic and anti-inflammatory frame
Insulin infusion targets glucose tight — hyperglycemia takes the blame
[Bridge]
Cefazolin one gram, sixty minutes before the skin
Redose every four hours if the operation pulls you in
Penicillin allergy — ninety percent are mislabeled, skin-test and delabel them
Oxytocin slow infusion post-delivery, carboprost for the refractory phlegm
Misoprostol sublingual, ergometrine raises pressure, know the contraindication
Dantrolene two point five per kilo — malignant hyperthermia obliteration
Magnesium sulfate tocolysis and seizure, bronchodilators open the constricted gate
Mannitol osmotic, furosemide for volume, hypertonic saline for ICP — calculate
[Chorus]
Другие препараты, запомни их все —
Antiemetics, steroids, коагуляция везде
Dantrolene is waiting, антибиотик в срок
Perioperative pharmacology — это наш урок
[Outro]
Every drug a role, every timing deliberate and precise
Reversal agents stocked, the prophylaxis balanced on a knife
Pharmacology не спит — it runs beneath the drape and blade
Know your drugs by mechanism, know the evidence that was made