Module 9 — Neoplastic Pathology

classical, piano, uk grime rap · 3:35

Listen on 93

Lyrics

[Verse 1]
H. pylori carving grooves into the antral wall
EBV hijacks the nucleus, diffuse type hits us all
Diet high in salt and nitrates, prior Billroth scarred the fold
CDH1 mutation — prophylactic gastrectomy, age told
Laurén said intestinal grows in glands, diffuse floats free
Signet rings don't form a mass, they infiltrate like debris
Linitis plastica, leather bottle, Borrmann Type Four's the worst
TCGA cut four subtypes — EBV, MSI first

[Chorus]
TNM staging, D-zwei Lymphadenektomie
Schneid die Ränder sauber — frozen section, can't be free
Resezione en bloc, margine netto, non cedere
HER2, PD-L1, MSI — la chiave per guarire
Stage it, cut it, sequence right — perioperative decree
FLOT vier Zyklen vor, vier nach — das ist die Therapie

[Verse 2]
Siewert Type One goes thoracic, CROSS trial leads the call
Type Two and Three go abdominal, gastric margins cover all
MAGIC showed periop chemo works, ECF around the knife
FLOT4 proved triplet docetaxel cuts deeper into life
INT-0116 — adjuvant chemorad when surgery stands alone
CLASSIC and ARTIST closed the Asian loop, capecitabine-owned
Claudin 18.2, a tight junction turned target, zolbetuximab's door
Checkpoint blockade for MSI-high — pembrolizumab at the fore

[Chorus]
TNM staging, D-zwei Lymphadenektomie
Schneid die Ränder sauber — frozen section, can't be free
Resezione en bloc, margine netto, non cedere
HER2, PD-L1, MSI — la chiave per guarire
Stage it, cut it, sequence right — perioperative decree
FLOT vier Zyklen vor, vier nach — das ist die Therapie

[Verse 3]
D2 dissection spares the spleen unless invasion's there
Dutch trial showed survival gain without the morbid snare
Subtotal beats total when the distal margin's clear
Laparoscopy first — cytology decides the frontier
Positive washings shift the stage, M1 without a mass
HIPEC and PIPAC — the evidence is thin as glass
Palliative resection only when obstruction bleeds or blocks
Early gastric, ESD criteria — submucosal depth unlocks

[Bridge]
GIST biologia — KIT o PDGFRA
Mitosi alte, grande dimensione — rischio che cresce già
Wedge resection, negative margin, no node dissection needed
Kapsel intakt — lass sie ganz — zerreißen ist verboten
Imatinib neoadjuvant shrinks the unresectable beast
Adjuvant three years post resection, high-risk recurrence ceased
D816V PDGFRA resists — switch to avapritinib's arm
Exon 9 KIT needs higher dosing — sequence before you harm

[Chorus]
TNM staging, D-zwei Lymphadenektomie
Schneid die Ränder sauber — frozen section, can't be free
Resezione en bloc, margine netto, non cedere
HER2, PD-L1, MSI — la chiave per guarire
Stage it, cut it, sequence right — perioperative decree
FLOT vier Zyklen vor, vier nach — das ist die Therapie

[Outro]
Lynch syndrome watches mismatch, FAP distorts the fundic gland
Li-Fraumeni, Peutz-Jeghers — hereditary demand
Surveil the remnant, biopsy deep, no margin left behind
Gastric cancer staged and sequenced — sharpen body, sharpen mind

← Module 8 — Benign and Inflammatory Pathology | Module 10 — Operative Techniques, Reconstruction, and Post-Gastrectomy States →