[Verse 1]
Milky white emulsion in the syringe,
Propofol hits fast — it's the lipid hinge,
Cytochrome P450 barely gets a say,
Hepatic and extrahepatic — clears away,
Drop in SVR, cardiac output falls,
Respiratory drive just hits the walls,
Apnea on induction, don't walk away,
Lidocaine in the line to dull the sting today,
And if you drip it days on end, watch the pH,
Metabolic acidosis — PRIS won't delay
[Chorus]
Propofol drops the pressure, ketamine climbs,
Etomidate holds steady — read the signs,
NMDA blocked, dissociation's near,
BIS is falling, burst suppression's clear,
Every agent carves a different trace —
Know your drugs before you take the case
[Verse 2]
Etomidate — the hemodynamic friend,
Steroid synthesis blocked around the bend,
11-beta-hydroxylase takes the hit,
Single dose cortisol suppression — just a bit,
Myoclonus fires without a seizure there,
Pretreat with benzo if you want to spare,
Septic shock or cardiac compromise in view,
Etomidate's the bridge to get you through
[Chorus]
Propofol drops the pressure, ketamine climbs,
Etomidate holds steady — read the signs,
NMDA blocked, dissociation's clear,
BIS is falling, burst suppression's near,
Every agent carves a different trace —
Know your drugs before you take the case
[Verse 3]
Ketamine speaks a dissociative tongue,
Phencyclidine cousin — thalamo-limbic rung,
Sympathomimetic surge, catecholamines flood,
Bronchodilation — useful if you could,
Sub-dissociative dosing, point-three per kilo,
Analgesic ceiling without the vertigo,
Emergence phenomena — vivid, strange, and bright,
Benzo coadministration smooths the night,
Awake fiberoptic? Ketamine keeps tone,
Airway intact — you're never left alone
[Bridge]
Thiopental's legacy lives in ECT's hall,
Methohexital still answers seizure's call,
Midazolam preops the anxious mind,
Remimazolam — organ-sparing by design,
Flumazenil reverses but don't trust the clock,
Resedation lurks when the antagonist stops,
Dexmedetomidine — alpha-two's quiet hand,
Bradycardia's the tax on this sedation plan,
Locus coeruleus quieted, cooperative airway won,
Awake intubation done without a benzodone
[Chorus]
Propofol drops the pressure, ketamine climbs,
Etomidate holds steady — read the signs,
NMDA blocked, dissociation's clear,
BIS is falling, burst suppression's near,
Every agent carves a different trace —
Know your drugs before you take the case
[Outro]
BIS below forty — deep suppression zone,
Burst suppression patterns etched in raw EEG bone,
Entropy measures order in the cortical hum,
Processed EEG guides the depth — don't fly numb,
Each molecule a lever on the conscious state,
Pharmacology sharp — that's how you operate