[Verse 1]
Step into the theatre, scrub and glove up tight
We're reading tissue under microscope light
Stomach lining damaged, rugae start to fade
Helicobacter pylori's the masquerade
Chronic gastritis, antral distribution
Type A hits the fundus, autoimmune solution
Intestinal metaplasia creeping through the wall
Goblet cells where columnar cells should call
This is dysplasia knocking at the door
Low grade to high grade, then carcinoma's floor
[Chorus]
G-M-D — Gross, Micro, Disease
Read the path report, interpret what you see
T-N-M — Tumour, Node, Metastasis
Stage it right, the staging is the basis
Mucosal layers, muscularis, serosa
The deeper it invades, the prognosis is closer
G-M-D — lock it in your memory
Pathology tells the story surgically
[Verse 2]
Small bowel, long and looping, villi standing tall
Crohn's disease comes creeping, transmural through the wall
Skip lesions spotted, cobblestone terrain
Non-caseating granulomas in the histological frame
Fistulae and strictures, fat wrapping round the gut
Knife-like fissures splitting deep, the lumen getting shut
Contrast it with coeliac, villous atrophy
Intraepithelial lymphocytes flood the biopsy
Marsh classification grades the damage clean
One through three, sub-totalling the scene
[Chorus]
G-M-D — Gross, Micro, Disease
Read the path report, interpret what you see
T-N-M — Tumour, Node, Metastasis
Stage it right, the staging is the basis
Mucosal layers, muscularis, serosa
The deeper it invades, the prognosis is closer
G-M-D — lock it in your memory
Pathology tells the story surgically
[Verse 3]
Colorectum now, adenoma to carcinoma track
Tubular, villous, tubulovillous — know the map
High-grade dysplasia, sessile serrated too
FAP mutations stack, APC breaks through
Duke's replaced by TNM but both deserve respect
T1 hits submucosa, T4 wrecks adjacent
Signet ring cells scattered, poorly differentiated
Microsatellite instability, Lynch syndrome implicated
Circumferential resection margin on the report
Positive margin, recurrence — the surgeon's last resort
[Bridge]
GIST — spindle cells and CD117 staining
Leiomyoma versus sarcoma, always worth explaining
Carcinoid tumours firing serotonin through
Chromogranin A lights up the immunohisto view
Peritoneal spread, omental caking on the scan
Read the radiology, then read the pathology plan
Every frozen section, every block and slide
Tells the operative decision deep inside — the tissue
[Chorus]
G-M-D — Gross, Micro, Disease
Read the path report, interpret what you see
T-N-M — Tumour, Node, Metastasis
Stage it right, the staging is the basis
Mucosal layers, muscularis, serosa
The deeper it invades, the prognosis is closer
G-M-D — lock it in your memory
Pathology tells the story surgically
[Outro]
Gross features first — ulcerated, polypoid, fungating mass
Micro follows — grade the cells, count the mitotic class
Interpret staging, correlate the clinical
Every pathology report becomes your surgical manual