Module 16 — Neuro-Oncology II: Extra-axial, Skull Base, and Sellar Tumors

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Lyrics

[Verse 1]
Arachnoid cap cells spinning slow,
meningioma seeds where membranes grow,
WHO grades one through three, mitoses count,
brain invasion tips the grade up to the mount,
NF2 mutation, convexity and spine,
TRAF7 and AKT1, skull base design,
SMO drives meningothelial at the base,
KLF4 secretory, a fibrous face,
radiation-induced, years after the beam,
a palimpsest of damage in the dural seam

[Chorus]
Simpson one through five, how much did you leave?
Grade one, coagulate the dura and sleeve,
Koos one through four for the angle and nerve,
devascularize early, embolize the curve,
match the approach to the pathology placed,
function preserved, no eloquence erased

[Verse 2]
Parasagittal sinus, Sindou's six-stage map,
sacrifice the sinus only when it's trapped,
olfactory groove stripped back from crista galli,
bilateral anosmia is the hidden penalty,
tuberculum sellae creeping toward the chiasm,
visual recovery hinges on the spasm,
medial sphenoid wing envelops the carotid,
clinoidal extension, cleavage plane morbid,
cavernous sinus, radiosurgery preferred,
petroclival tumors, every cranial nerve stirred

[Chorus]
Simpson one through five, how much did you leave?
Grade one, coagulate the dura and sleeve,
Koos one through four for the angle and nerve,
devascularize early, embolize the curve,
match the approach to the pathology placed,
function preserved, no eloquence erased

[Verse 3]
Retrosigmoid, translabyrinthine, middle fossa plane,
Gardner–Robertson tells you what the cochlea can sustain,
serviceable hearing, T-one small, attempt to save,
labyrinthine route surrenders sound to spare the facial wave,
NF2 bilateral, bevacizumab slows the tide,
facial nerve dissection under monitoring's guide,
glomus jugulare, Fisch classification,
screen catecholamines before embolization,
chordoma carries brachyury in its cell,
proton therapy reaches where the photons fell,
epidermoid gleams like nacre in the angle's fold,
endolymphatic sac tumor, VHL enrolled

[Bridge]
Now the sella opens, pituitary terrain,
six axes humming, hypothalamic refrain,
prolactinoma answers dopamine's call,
cabergoline contracts before you cut at all,
acromegaly, IGF-one still climbing high,
Cushing's cortisol, a dexamethasone reply,
transsphenoidal corridor, the endoscope descends,
binostril four-hand, angled lens ascends,
craniopharyngioma, adamantinomatous kind,
CTNNB1 mutation, calcified and lined,
papillary variant, BRAF V600E strand,
BRAF-MEK inhibition, a pharmaceutical hand,
Rathke's cleft cyst whispers midline quiet,
a cystic epiphenomenon, rarely needs a riot

[Chorus]
Simpson one through five, how much did you leave?
Grade one, coagulate the dura and sleeve,
Koos one through four for the angle and nerve,
devascularize early, embolize the curve,
match the approach to the pathology placed,
function preserved, no eloquence erased

← Module 15 — Neuro-Oncology I: Intra-axial Tumors | Module 17 — Hydrocephalus and CSF Disorders →